Preheat your oven to 350ºF (180ºC or Gas 5).
Make the Garlic Butter Sauce
Whisk together the butter, worcestershire sauce, poppy seeds, white sesame seeds, garlic powder, minced onion, and salt and pepper together in a small bowl. Set aside for later.
Make the Sliders
Place the bottom halves of the slider buns onto your baking dish or rimmed baking sheet. Toast the buns for 2-3 minutes in the preheated oven and remove.
Spread the aioli or mayonnaise over the bottom halves of the buns, then layer with the roast beef, slices of cheese, shredded mozzarella, and caramelized onions, if using.
Top with the top halves of the slider buns, then use a pastry brush or silicone brush to slather the melted garlic butter sauce on top of the buns. Don't be stingy!
Put the roast beef sliders into the preheated oven and bake for up to 15 minutes, until the tops are golden brown and the cheese is nice and melty.
Cut between each slider with a serving spatula and serve with the rich, beefy au jus.
Make the Beef Au Jus
Melt the butter in a saucepan over medium-high heat.
Whisk in the beef broth, beef base, and worcestershire sauce until well combined.
Bring to a boil, then reduce to medium-low and simmer for about 15-20 minutes until the au jus reduces by half.
Pour into a heat-safe bowl for dipping.